# Used HPLC buyer's guide — the conversation you want with a 15-year refurb tech before wiring money

**Date:** 2026-04-23
**Scope:** Agilent 1050 → 1260 Infinity II, with cross-vendor notes (Shimadzu, Waters, Hitachi). Module-level failures, pre-purchase inspection, software traps, aftermarket parts, refurb vendors, DIY refurb scope, decision framework.
**Cross-refs:** [`hplc-used-prices.md`](../04-equipment-market/hplc-used-prices.md) · [`red-flags-used.md`](../04-equipment-market/red-flags-used.md) · [`market-overview.md`](../04-equipment-market/market-overview.md) · [`consumables-costs.md`](../04-equipment-market/consumables-costs.md) · [`budget-tier-silver.md`](../05-home-lab-setup/budget-tier-silver.md) · [`sop-estradiol-valerate-hplc.md`](sop-estradiol-valerate-hplc.md)
**AI disclosure:** compiled by an AI agent using the structured claim format from `/workspace/overview/RESEARCH-BEST-PRACTICES.md`. Numeric claims carry C1–C5 tiers. Unflagged prose is inference; treat as C3 unless supported. Verify part numbers and prices against Agilent/vendor sites before wiring money.

---

## TL;DR

1. **Buy an Agilent 1100 if your budget is under $18k.** The 1100 is the single best instrument-for-dollar HPLC on the used market. Parts are abundant, ChemStation B.04.03 is the last compatible rev and most 1100 sellers include a working PC with the license, and refurbers compete hard enough that certified units with a warranty are genuinely priced.
2. **Buy a 1260 Infinity I or II if your budget is $25–50k.** Same modular architecture, better electronics, OpenLab CDS, still refurbable at home.
3. **Do not buy a Waters Alliance 2695 unless you have a transferable Empower license in hand.** The hardware is legendary; the license trap is real and can cost more than the hardware.
4. **"Powers on" means nothing.** Demand a test chromatogram and lamp burn hours before paying. A seller who won't run a caffeine injection for you is a seller who knows something they aren't telling you.
5. **Budget 20–40% over the sticker price** for columns, mobile phase, a backup D2 lamp, an install qualification, and the 200 small consumables (fittings, frits, guard cartridges) that don't ship with the instrument.

Agilent 1100 end-of-support was **2026-01-31** — Agilent no longer sells OEM parts or service contracts. Third-party parts remain abundant (Idex, Sciencix, Restek, Cole-Parmer, JM Science). EOL does not make the instrument useless; it does make OEM-only part guarantees dead, and it pushed used prices down ~15–25% in Q4 2025 (see [hplc-used-prices.md](../04-equipment-market/hplc-used-prices.md)).

---

## 1. Agilent HPLC generation map

This is the reference table. Memorize it before you start reading listings.

| Generation | Years | Signature | Software (terminal) | Community-lab verdict |
|---|---|---|---|---|
| **1050** | 1989–1995 | Sealed-piston pumps, older firmware, not modular in the 1100 sense | ChemStation A.xx (Win 3.1 / 95 / NT); effectively unsupported | Avoid unless you collect vintage. Parts drying up. |
| **1100** | 1995–2007 | Modular (CAN bus), distinctive cream/grey body, LAN+GPIB modules | **ChemStation B.04.03 SP2** (last-compatible; Agilent EOS 2026-01-31) | **10/10.** Sweet spot for a home lab. |
| **1200** | 2007–2012 | Same modular body, better electronics, "SL" high-pressure variants | ChemStation B.04.03 supports 1200 also; OpenLab CDS C.01 works | 9/10. Slightly more expensive than 1100 for marginal gain. |
| **1260 Infinity I** | 2012–2017 | Refreshed electronics; UHPLC-capable modules (G4220A) | OpenLab CDS C.01.07+ required for newer modules | 9/10. Current-gen methods compatible. |
| **1260 Infinity II** | 2017–present | Integrated InfinityLab architecture, InfinityLab DAD WR (G7117B), RFID lamps | **OpenLab CDS C.01.10+**; license aggressively site-locked | 8/10. Best capability, worst license bureaucracy. |
| **1290 Infinity I/II** | 2010–present | UHPLC (1200 bar / 1300 bar), sub-2 µm columns | OpenLab CDS | Overkill for a community HRT lab; avoid unless you have a reason. |

### Module nomenclature (1100 era — memorize these numbers)

| Code | Module | Notes |
|---|---|---|
| **G1310A** | Isocratic pump | Single-solvent. Not useful for gradient methods; cheap. |
| **G1311A** | Quaternary pump | 4-solvent low-pressure gradient. Most common, most forgiving. |
| **G1312A** | Binary pump | 2-solvent high-pressure gradient. Better for UHPLC-style reproducibility; slightly more failure-prone. |
| **G1313A** | Standard autosampler (ALS) | 100-vial capacity. |
| **G1329A** | Thermostatted ALS | Same with Peltier deck; pair with G1330A/B thermostat. |
| **G1314A/B/C/D/E/F** | VWD (variable-wavelength detector) | A/B = 1100 era; C/D = 1200 era; E/F = 1260. Single-wavelength. |
| **G1315A/B/C/D** | DAD (diode-array detector) | B is 1100-peak; C/D are 1200/1260. DAD gives you full UV spectrum per peak. |
| **G1316A/B/C** | Column compartment (thermostat) | A = basic; B = dual-loop; C = identification module w/ RFID. |
| **G1322A** | Degasser (4-channel vacuum) | Older style; sometimes fails silently. |
| **G1379A/B** | Micro vacuum degasser | Replaced G1322A in later 1100s. |

### 1200 / 1260 notable modules

| Code | Module | Notes |
|---|---|---|
| G4220A | 1290/1260 binary pump (1200 bar) | Requires newer ChemStation or OpenLab. |
| G7112B | 1260 Infinity II binary pump | OpenLab-only. |
| G1367E / G7129A | 1260 autosampler / multisampler | Larger vial capacity, sample cooling. |
| G7115A / G7117B | 1260 Infinity II DAD WR | InfinityLab style; RFID D2 lamps. |

### Why 1100 is the sweet spot

**Claim:** Agilent end-of-support for 1100 series effective 2026-01-31.
- **Confidence:** C1
- **Source:** https://www.chromforum.org/viewtopic.php?t=26656 ; multiple Agilent community threads 2025–2026
- **Date checked:** 2026-04-22
- **Notes:** EOS = Agilent stops selling new OEM parts and drops factory service contracts. Third-party parts (Idex, Sciencix, Restek, JM Science, Cole-Parmer) continue indefinitely. Used-market prices dropped ~15–25% in Q4 2025 in anticipation of this date.

**Claim:** ChemStation B.04.03 is the last revision compatible with the 1100 series, and Agilent has indicated it will not receive further patches after 1100 EOS.
- **Confidence:** C2
- **Source:** https://community.agilent.com/technical/lc/f/forum/11400/chemstation-software-for-agilent-1100-hplc ; https://www.chromforum.org/viewtopic.php?t=81384
- **Date checked:** 2026-04-22
- **Notes:** B.04.03 SP2 runs on Windows 10 Pro 64-bit; also runs in Win 7 32/64-bit. It does not run on Windows 11 without unsupported workarounds. Sellers bundling "ChemStation 4.3" in their listings (Marshall Scientific et al.) mean B.04.03.

Parts depth, license freedom, and the fact that nearly every refurber has 1100 hardware on the shelf is why the community lab verdict is 10/10. Refurb vendors (Marshall Scientific, Conquer Scientific, New Life Scientific) all price certified 1100 DAD stacks in the $12–17k band with a warranty — see §8.

---

## 2. Module-level failure modes

This is what fails, how it presents, what it costs to fix, and whether you can do it at home. The source for Agilent part numbers is the Agilent parts catalog; verified 2026-04-22.

### 2.1 Pump (G1311A quaternary / G1312A binary)

**Pump piston seals — the #1 thing to fail.**

| Failure | Symptom | Fix | Cost | Home-doable? |
|---|---|---|---|---|
| Worn primary seal | Low-pressure-side leak from pump head drain; pressure pulsation >2%; ratio fail on gradient test | Replace primary seal | Agilent **5063-6589** ~$150–200 pack of 2 (Agilent store / distributors 2026-04-22; https://www.agilent.com/store/en_US/Prod-5063-6589/5063-6589 — round-2 correction R2-M11 from earlier "$50–80" estimate which is stale or referred to a single seal) | **Yes.** 1 hour, 1/4" wrench + 4-mm hex, service video on Agilent Community. Seal wear-in protocol: 1 hr at 300 bar w/ IPA. |
| Worn piston (scored) | Seal swap doesn't fix; new seal fails fast | Replace sapphire piston (5063-6586 or equivalent) | $100–300 | Yes with steady hands. |
| Failed active inlet valve (AIV) | Gradient ratios wrong; pump won't prime; air in pump head | Replace AIV cartridge (5062-8562) or full AIV assembly (G1312-60010) | Cartridge ~$150; full AIV ~$300–400 | **Yes.** 20 minutes. Agilent LC Portal article KP680. |
| Failed outlet ball valve | Pressure won't build; pump won't hold steady | Replace outlet valve assembly | $100–200 | Yes. |
| Seized / damaged piston stroke motor | Pump fails to start; grinding; pressure = 0 | Replace stroke motor or exchange pump head | $500–1500 | No. Ship to refurber. |

**Claim:** Agilent 1100 primary pump seal kit (part 5063-6589, pack of 2) is still listed on the Agilent store as of 2026-04-22.
- **Confidence:** C1 (Agilent store page is authoritative; price fluctuates and was not captured at the penny level)
- **Source:** https://www.agilent.com/store/en_US/Prod-5063-6589/5063-6589
- **Date checked:** 2026-04-22

**Claim:** AIV cartridge part number is 5062-8562; full AIV without cartridge is G1312-60010 (or G1312-60025 — a variant).
- **Confidence:** C2
- **Source:** https://www.scinteck.com/store/p1615/G1312-60025.html ; cross-referenced with Agilent LC Portal article KP680
- **Date checked:** 2026-04-22

**Diagnostic to run on a demo:** "Pressure ripple test." Ask the seller to run 1.0 mL/min of HPLC-grade methanol through a dummy column (or 5 m of 0.17 mm ID capillary as a restrictor) for 10 min. Pressure should be stable within **<2% ripple** peak-to-peak. If you see 5%+ pulsation, the seal or piston is shot. If pressure fails to build past ~100 bar, AIV or check valve.

### 2.2 Autosampler (G1313A / G1329A)

| Failure | Symptom | Fix | Cost | Home-doable? |
|---|---|---|---|---|
| Worn rotor seal | Carryover between injections; pressure drop on inject; crosstalk | Replace rotor seal (0101-1416 or kit) | Kit $200–400 | **Yes.** 30 minutes. |
| Bent needle | Poor reproducibility; septum coring; maybe physically visible | Replace needle (G1313-87201) | $75–150 | Yes. 10 minutes. |
| Needle seat corrosion | Leak at injection; injection pressure high | Replace needle seat (01078-87302) | $100–250 | Yes. |
| Metering syringe wear | Injection volume CV >2% | Rebuild metering kit | $150–400 | Yes with patience. |
| Z-drive / transport encoder | Random injection failures; "needle position" error | Service visit | $400–1500 | No. Shop job. |

Run a **six-replicate injection** on a known standard (e.g. 0.1 mg/mL caffeine in methanol:water 50:50) to qualify an autosampler. Area CV must be < 1.0% on a working unit; reproducibility >2% means metering or rotor is tired.

### 2.3 VWD (G1314A/B/C/D) and DAD (G1315A/B/C/D)

| Failure | Symptom | Fix | Cost | Home-doable? |
|---|---|---|---|---|
| **D2 lamp aging** | Signal drop; "lamp intensity low"; noisy baseline | Replace D2 lamp | **$425–800** depending on source (see below) | **Yes. 10 minutes, plug-and-play.** |
| Flow cell fouling | Baseline noise not improved by solvent change; drifting baseline on injection | Clean (MeOH flush → 0.1 N HNO3 for ionic deposits → MeOH rinse) or replace flow cell | Cleaning free; new cell $500–1500 | Cleaning yes; replacement yes but finicky. |
| Tungsten visible-range lamp aging (DAD only; 190–800 nm) | Reduced sensitivity above 500 nm | Replace W lamp | $200–400 | Yes. |
| Failed photodiode segment (DAD) | Spectrum has dead zones | None (full DAD exchange) | Swap DAD module | No for home. |
| Misaligned wavelength calibration | Peak maxima at wrong λ | Run holmium oxide standard; instrument-guided re-cal | Free | Yes with a holmium filter (~$200). |

**D2 lamp pricing (as of 2026-04-22):**

| Source | Part | Typical price | Rated life |
|---|---|---|---|
| Agilent OEM long-life | 5190-0917 (1260-era, 8-pin RFID) | ~$700–900 (Agilent store; not directly capturable 2026-04-22 — price hidden behind login) | 2000 h |
| Agilent OEM standard | 2140-0813 or 2140-0820 (1100/1200 era) | ~$600–800 | 1000–2000 h |
| JM Science (Agilent-style) | — | $400–600 | 2000 h |
| Cole-Parmer branded | 1194113 (A/B series DADs, G1315/G1365) | ~$500–650 | 1000 h (2000 h long-life) |
| Restek 25261 / 25888 / 25399 | — | $400–600 | 1000–2000 h |
| Azzota / LabShops | OEM-equivalent | **$425.99 / $599** | ~1000 h standard; 2000 h long-life |

**Claim:** Azzota OEM-equivalent D2 lamp for 1100/1200 DAD is $425.99 / $599 at labshops.com as of 2025-2026.
- **Confidence:** C2
- **Source:** https://labshops.com/products/p_865-deuterium-lamp-agilent-1100-and-1200-hplc-detector-dad
- **Date checked:** 2026-04-22

**Claim:** Agilent long-life D2 lamp for 1260/1290 DAD (5190-0917) is rated 2000 h per Agilent.
- **Confidence:** C1
- **Source:** https://community.agilent.com/knowledge/lc-portal/kmp/lc-articles/kp1485.replacing-the-deuterium-lamp-in-1290-and-1260-infinity-diode-array-detectors
- **Date checked:** 2026-04-22

**Ask every seller:** "What's the lamp burn hours?" It's in the detector firmware, visible from ChemStation Diagnostics. A seller who refuses or "doesn't know" is hiding something. 1500+ hours means budget a lamp within a year; 2000+ hours means replace before first use.

**Diagnostic test for detector:** Inject 5 µL of **1.0 mg/mL caffeine** in methanol:water 50:50 with MeOH:water 50:50 isocratic mobile phase at 1.0 mL/min on a 150×4.6 5 µm C18, monitor at 273 nm. Expect a sharp peak at ~3–5 min retention and peak height ~0.5–1.0 AU on a 20 mm path cell. Baseline noise **< 0.0001 AU** on a fresh lamp. > 0.0005 AU means lamp or cell cleaning needed.

### 2.4 Column compartment (G1316A)

| Failure | Symptom | Fix | Cost | Home-doable? |
|---|---|---|---|---|
| Temperature drift | Can't hold 40±0.5 °C for 20 min | Replace Peltier module or thermistor | $300–800 | Yes (moderate). |
| Heat exchanger leak | Mobile phase pooling in compartment floor | Replace heat exchanger loop | $200–400 | Yes. |
| Column identification RFID reader failure (C-variant only) | Column-ID feature stops working but heating OK | Usually cosmetic; ignore or swap TCC | $0 for ignore | N/A |

### 2.5 Degasser (G1322A / G1379A/B)

| Failure | Symptom | Fix | Cost | Home-doable? |
|---|---|---|---|---|
| Vacuum pump wear | Pump fails to achieve vacuum; bubbles in mobile phase lines; baseline oscillations | Replace internal vacuum pump module | ~$400–700 | Yes with patience. |
| Degas membrane leak | Mobile phase leaks into vacuum chamber | Replace membrane assembly | $400–600 | Yes. |
| Total degasser failure | No vacuum | Bypass with external He sparging (cheap and reliable) | $50 for sparge tubing + $50 He cylinder rental + $150/month He | DIY workaround. |

**Quick trick:** if the degasser is dead and the method doesn't require aggressive degassing (most isocratic methods don't), you can bypass it entirely and use **helium sparging** of mobile phase bottles via a stainless frit — works well for analytical-scale methods. Not GMP-compliant but perfectly fine for community-lab identity/purity assay.

---

## 3. Pre-purchase inspection checklist

Print this. Take it to the demo. If you can't demo in person, send it to the seller as questions with photo requests.

### 3.1 Visual (takes 5 minutes, reveals 80% of problems)

- [ ] **Solvent trails / crust on pump head.** Dried methanol crust = chronic leak. Salt deposits (white crust) = phosphate buffer was left in without flush = corrosion risk.
- [ ] **Rust or corrosion on frames, cabling, or connector pins.** This is the single worst red flag — indicates water damage / bad storage. Walk away.
- [ ] **Burnt smell / discoloration on circuit boards.** Electronics damage. Walk away.
- [ ] **Missing tubing, loose fittings, finger-tight swagelok left loose.** Tells you the seller didn't bother to package it properly — probably didn't run it either.
- [ ] **Column compartment floor clean?** Any mobile-phase residue indicates a live leak somewhere upstream.
- [ ] **D2 lamp area — check for discoloration of the lamp window.** Yellow/brown = lamp aged past end-of-life.
- [ ] **Serial number plates present on every module.** Missing S/N = scavenged or fake; required for software registration.
- [ ] **"Yellow envelope" ChemStation license sticker on the PC.** If it's not physically there, the license is void and you're buying hardware only.

### 3.2 Power-on test

- [ ] Every module boots (no amber/red status LED beyond normal startup).
- [ ] ChemStation (or OpenLab) recognizes all modules. Each module should appear in the instrument configuration dialog with a firmware revision and S/N.
- [ ] Run the built-in **Instrument Self-Test** (ChemStation Diagnostics → Self-Test). Every module must pass.
- [ ] Note lamp burn hours, pump primary-seal hours if tracked, injection count on autosampler.

### 3.3 Functional tests (the real acceptance criteria)

- [ ] **Pump ratio test:** 25/25/25/25 quaternary gradient with solvent A = MeOH, B = MeOH + 0.1% acetone UV marker, C = MeOH, D = MeOH. Step-up each channel individually, watch 265 nm absorbance. Ratios should match nominal ±1%.
- [ ] **Pump pressure ripple test:** steady 1.0 mL/min through a restrictor for 10 min. <2% pressure ripple peak-to-peak. Absolute pressure stable within ±1 bar.
- [ ] **Autosampler precision:** 6 replicate injections of 0.1 mg/mL caffeine. Area %RSD < 1.0%. Retention time SD < 0.02 min.
- [ ] **Detector linearity:** single-point check — 1 mg/mL caffeine should produce ~2 AU at 273 nm on a 10 mm path cell, ~4 AU on a 20 mm high-sensitivity cell. Baseline noise < 0.0001 AU.
- [ ] **Detector wavelength accuracy:** scan the holmium oxide reference peaks at 361, 454 nm. Should be ±1 nm.
- [ ] **Column compartment:** set 40 °C, 20-min hold. Internal sensor readout must hold ±0.5 °C. Verify with an independent thermocouple in the column compartment air space.
- [ ] **End-to-end chromatographic test:** inject the caffeine standard above on a standard 150×4.6 5 µm C18 column (Phenomenex Luna or equivalent), isocratic 50:50 MeOH:water, 1.0 mL/min, 40 °C, 273 nm. Expect a symmetrical peak (tailing factor < 1.5) at ~3–5 min with RT SD < 0.02 min across 6 injections.

### 3.4 Software & interface

- [ ] **ChemStation revision.** For 1100/1200, must be B.04.03 (ideally SP2). For 1260 I, ChemStation B.04.03 works for most modules; OpenLab CDS C.01.07+ for the newer ones. For 1260 II, OpenLab CDS C.01.10+.
- [ ] **License dongle present** (USB hardware key on older systems) — some ChemStation revisions require it.
- [ ] **PC boots, admin password known, user accounts accessible.**
- [ ] **GPIB or LAN interface card present** (1100 pre-LAN modules use GPIB/HP-IB).
- [ ] **ChemStation instrument method library files (.M) and sequence files (.S) present** — not strictly required, but a sign the seller actually ran the thing.
- [ ] **Physical manuals** present — CDs, binders, or scans. Especially the "Reference Manual" and "Service Manual" for each module.

### 3.5 Paperwork

- [ ] IQ/OQ/PQ certificates (if any — refurbishers may include).
- [ ] Calibration records for the detector lamp, autosampler metering volume.
- [ ] Service history log (Agilent service center stamps, if applicable).
- [ ] Warranty documentation (refurbishers usually 90–180 days).

---

## 4. Software license transfer — the trap

Software bureaucracy has killed more used HPLC deals than bad hardware.

### 4.1 ChemStation (perpetual license era: 1100 + early 1200)

ChemStation was sold as a perpetual license. The license is attached to the physical license sticker — a yellow envelope with a license ID and key. The license **travels with the hardware** when sold, provided the seller includes the sticker.

- **If sticker is present:** the license is valid on any PC you install the software on, using that key. You can re-install ChemStation B.04.03 on a fresh Windows 10 Pro machine from the Agilent CD (or an ISO pulled from community archives) and enter the license key; it activates.
- **If sticker is missing:** Agilent's official position is the license is non-transferable without it. In practice you can sometimes negotiate a replacement license with Agilent for $2–5k. In other cases they'll decline and quote you a new license (~$5k–15k). The missing-sticker outcome is unpredictable — price it as if the license is void.

**Claim:** ChemStation B.04.03 SP2 runs natively on Windows 7 (32/64-bit) and Windows 10 Pro 64-bit.
- **Confidence:** C2
- **Source:** https://www.chromforum.org/viewtopic.php?t=81384 ; Agilent release notes
- **Date checked:** 2026-04-22
- **Notes:** does not run officially on Windows 11. Community users report it can be coerced via compatibility mode but driver signing (GPIB especially) is a pain point. Recommend sticking with a dedicated Win10 Pro 64-bit data station.

### 4.2 OpenLab CDS (1260 I, 1260 II, newer)

OpenLab is a site-licensed / subscription-y model. License is bound to a site license file and a license server (or standalone workstation license). Transferring means the seller **deactivates** the license at their end and you **activate** at yours, through Agilent's license portal.

- In practice: refurbishers handle this. Private-party sales between end users often involve a painful 2–6 week bureaucratic lap with Agilent Customer Service.
- Some listings ship with the PC pre-imaged with OpenLab running; Agilent has limited enforcement of "ghost" installations but you'd be technically non-compliant.
- Subscription OpenLab (newer model) is *month-to-month* and can be swapped to your account directly at Agilent list price — ~$4–8k/year depending on the tier.

### 4.3 PC requirements

| Generation | PC OS support | Interface | Hardware notes |
|---|---|---|---|
| 1100 (early) | Win 2000 / XP (orig), Win 7, Win 10 Pro 64-bit w/ B.04.03 SP2 | GPIB (HP-IB) card required for older modules | GPIB card (Keysight 82350B or 82357B USB-GPIB) ~$200–500 used |
| 1100 (late) / 1200 | Win 7 / 10 Pro 64-bit | LAN (G1369A interface module) | LAN cable sufficient |
| 1260 I | Win 10 Pro 64-bit | LAN | OpenLab CDS specific hardware reqs |
| 1260 II | Win 10 / 11 | LAN | Agilent-certified workstation preferred |

**Do NOT** buy a 1100 and expect to run ChemStation on your existing daily-driver Windows 11 laptop. You will spend a weekend fighting driver signing. Dedicate a Windows 10 Pro machine. The refurbishers ship dedicated Dell OptiPlex or HP EliteDesk PCs with everything configured — that's the path of least resistance.

### 4.4 Waters Empower — the real trap

Waters Empower is the standard for Waters Alliance/Acquity hardware. Waters takes a **hard line** on license transfers: the terms of use require the seller to deinstall the license before you can use it, and they won't issue a new license key to a secondary buyer without paying a relicensing fee (historically $5–15k).

**Claim:** Waters treats Empower licenses purchased through third-party resellers as non-transferable; secondary buyers typically need to purchase a new Empower license from Waters direct.
- **Confidence:** C2
- **Source:** https://www.chromforum.org/viewtopic.php?t=17194 ; https://www.waters.com/nextgen/us/en/products/informatics-and-software/chromatography-software/empower-software-solutions.html
- **Date checked:** 2026-04-22

Workarounds:
1. **Chromeleon (Thermo)** — some users run Waters Alliance hardware through Thermo Chromeleon via third-party driver packs. Legal gray area; works.
2. **OpenChrom / ChromPerfect / Clarity CDS** — free and paid third-party CDS that support Waters hardware via generic drivers. Best option for budget labs.
3. **Buy from a lab that Waters will re-license** — rare, usually requires Waters' blessing upfront.
4. **Empower Subscription** — Waters now sells month-to-month subscription Empower directly. Ongoing cost.

Bottom line: if you're looking at a Waters Alliance 2695 for $5–7k, budget $0 for software (use Clarity) or $10k+ for a Waters relicense. Plan accordingly.

### 4.5 Shimadzu LabSolutions

More lenient than Waters. Licenses are tied to the instrument serial + a software activation; transfers are usually possible with a Shimadzu support call. Community reports activation works after a re-install in most cases.

---

## 5. Aftermarket parts ecosystem

You will buy parts from these people, not Agilent, after EOS in January 2026.

| Vendor | Specialty | Notes |
|---|---|---|
| **Idex Health & Science** | Fittings, valves, pumps, tubing | Made the OEM valves in many HPLCs; their aftermarket is often identical to what Agilent ships. |
| **Sciencix** | Agilent-equivalent parts (pumps, lamps, seals, PEEK) | https://sciencix.com/ — 40–70% OEM price; quality is generally very good. |
| **JM Science** | Agilent-style lamps, LC consumables | Reliable, based in NY. |
| **Cole-Parmer** | Branded OEM-equivalent consumables (D2 lamps, fittings) | Part lookup by Agilent p/n is easy; good catalog; prices 20–40% below Agilent. |
| **Restek** | Columns + aftermarket consumables | Strong reputation for columns and some instrument consumables. |
| **Phenomenex** | Columns (Luna, Kinetex, Gemini) | Widely used by community labs. Any HPLC with 1/16" fittings accepts their columns. |
| **Waters** | Columns (XBridge, Atlantis, CORTECS) | Columns fit any HPLC regardless of hardware brand. |
| **Supelco / Sigma-Aldrich** | Columns + reference standards | Good for method transfer from USP monographs. |
| **ImtakT USA** | Japanese-manufactured columns; some replacement parts | Specialty columns (Unison, Cadenza). |
| **Sartorius / Millipore** | Mobile-phase filters (0.2 µm, 0.45 µm) | Lab-grade filtration supplies. |
| **Allied Filter Systems** | Pre-made filter assemblies | Good for large-volume mobile phase. |

**Scrapper-unit strategy:** sometimes it's cheaper to buy a whole "as-is / for parts" 1100 module on eBay ($500–1500 for a pump or detector) and cannibalize it than to buy individual parts at OEM or aftermarket. A dead 1100 VWD makes an excellent lamp-and-flow-cell donor for a working one. Community forum wisdom: keep one "parts" 1100 in the corner if you run an in-house lab at any scale.

---

## 6. Refurb vendor ecosystem

Who to buy from, and their relative risk/reward profile. Prices verified on 2026-04-22 where cited.

### 6.1 Certified refurbishers (full warranty, higher price)

**Marshall Scientific** (Hampton, NH) — https://www.marshallscientific.com/

- Deep 1100 / 1200 / 1260 Infinity I inventory; also sells Thermo, Shimadzu, Waters.
- 180-day parts & labor warranty standard.
- Ships with a pre-configured Windows 10 Pro PC with ChemStation 4.3 installed.
- Good documentation: modules listed with G-codes, PC spec listed, lamp replacement history usually not listed.

**Claim:** Marshall Scientific lists Agilent 1100 HPLC with DAD (G1311A quat + G1329A ALS + G1330B therm + G1315B DAD + G1316A TCC + G1379A degasser + Dell OptiPlex 7050 PC + ChemStation 4.3 + Lab Advisor) at **$15,530 sale (regular $16,490)** with 180-day full parts & labor warranty as of 2026-04-22.
- **Confidence:** C1
- **Source:** https://www.marshallscientific.com/Agilent-1100-HPLC-DAD-System-p/ag-1100d.htm
- **Date checked:** 2026-04-22

**Claim:** Marshall Scientific lists Agilent 1260 Infinity I with DAD (Deal-of-the-Month) at **$39,995 sale (regular $49,290)** with 180-day warranty as of 2026-04-22.
- **Confidence:** C1
- **Source:** https://www.marshallscientific.com/Agilent-1260-Infinity-I-HPLC-System-w-DAD-p/ag-1260hplcdad.htm
- **Date checked:** 2026-04-22

**Claim:** Marshall Scientific lists Agilent 1260 Infinity I with VWD (G1312B binary + G1329B ALS + G1330B therm + G1316A TCC + G4225A HPD + G1314F VWD + Win 11 Pro 64-bit PC + ChemStation 4.3) at **$38,490 sale (regular $47,490)** as of 2026-04-22.
- **Confidence:** C1
- **Source:** https://www.marshallscientific.com/Agilent-1260-Infinity-I-HPLC-System-w-VWD-p/ag-1260hplcvwd.htm
- **Date checked:** 2026-04-22

**Claim:** Marshall Scientific lists Agilent 1260 Infinity II LC system (G7112B binary + G7115A DAD WR + G7167A multisampler + G7116B MCT + G1170A UVD + MassHunter Workstation Software) at **$50,490 sale (regular $60,190)** as of 2026-04-22.
- **Confidence:** C1
- **Source:** https://www.marshallscientific.com/Agilent-1260-Infinity-II-LC-System-p/ag-1260.htm
- **Date checked:** 2026-04-22

**Conquer Scientific** (San Diego, CA) — https://conquerscientific.com/

- Similar niche. Founded 2003.
- Standard warranty **30 days**; extended 90 days with onsite installation option.
- Typical 1100 pricing $8–15k depending on configuration; 1200/1260 $15–30k.
- Sells preparative 1100 systems for scale-up.

**Claim:** Conquer Scientific lists Agilent 1100 Series Preparative HPLC at $15,900 (with financing option); offers 30-day standard warranty, extended 90-day with onsite install.
- **Confidence:** C2
- **Source:** https://conquerscientific.com/product/agilent-1100-series-preparative-hplc-system/
- **Date checked:** 2026-04-22

**New Life Scientific** (Ohio) — full-service refurbisher, LabX-front presence, warranty typically 60–180 days.

**American Laboratory Trading (ALT)** — LabX frontend, multiple refurb 1100 / 1200 / 2695 listings; usually 60–90 day warranty.

**Scientific Equipment Repair / Arc Scientific / GenTech / SpectraLab** — LabX-front refurbishers with variable warranty terms (read fine print).

### 6.2 Broker / listing aggregators

**LabX.com** — not a reseller; a listing broker. Item IDs beginning "DIS-" are dealer listings; "LV-" are lab-vacating listings. Price drift is normal — listings update asynchronously. **M6 case study:** LabX listing DIS-49376 (Biotech Equipment Sales, CA, Agilent 1100 HPLC) was listed at **$10,500 on 2025-05-09** and **$24,500 on 2026-04-22** — same listing, seller repriced 2.3× upward over 11 months. Moral: always click through to the current listing; never quote a cached price.

**EquipNet** — auction-style and fixed-price. Heavier on surplus/decommission lots from pharma and biotech. Good for cheap Waters hardware; be alert to shipping logistics.

**International Equipment Trading Ltd (IET)** — old-school broker, Illinois; still in business. More common in mass spec than HPLC.

### 6.3 eBay

- **"Powers on"** listings: $4,000–8,000 for partial Agilent 1100 stacks (pump + detector, no ALS, no PC). Zero warranty. Buy only if you are willing to eat a total loss or have skills to refurb.
- **"Fully refurbished & tested"** by eBay sellers: $8,000–15,000 for Agilent 1100 stacks with PC. Some sellers (e.g., Sonoran Surplus) are well-regarded; some are cowboys.
- Module-level ("G1312A binary pump, tested"): $500–1500 per module. Great for parts or to upgrade.

### 6.4 University / pharma surplus auctions

**GovDeals** (state/municipal), **Hilco** (commercial), university surplus sites — sometimes extraordinary deals ($2–5k Agilent 1100 stacks) and sometimes pure scrap. **Rule:** inspect in person before bidding, or don't bid.

### 6.5 Craigslist / local auctions

Rare but real. A lab that's closing will post a full HPLC stack on Craigslist for $3k because they don't know what it's worth. If you have test-before-buy access, it's the best value on the market.

### 6.6 Certified vs as-is — the price premium

| Category | Price premium over as-is eBay | What you get |
|---|---|---|
| **Certified refurb** (Marshall, Conquer, ALT) | +30–80% | Warranty, pre-tested, PC configured, ChemStation license clean, install support |
| **"Refurbished" LabX broker listing** | +10–40% | Variable. Read the warranty. Sometimes just cleaned-up as-is. |
| **"Powers on" eBay** | baseline | You're the QA. Budget 20–40% additional for surprise parts. |
| **Surplus auction** | baseline or below | Lottery. Inspect before bidding. |

For a first-time HPLC buyer at a community lab, **certified refurb is almost always the right call.** The 30–80% premium buys a warranty and eliminates the scenario where you're $8k in and the pump is dead and the seller has ghosted you.

---

## 7. DIY refurb — what's home-doable and what isn't

### 7.1 Home-doable (every 1100 owner should learn these)

| Task | Time | Cost | Difficulty |
|---|---|---|---|
| Pump piston seal swap | 1 hour | $50–80 | Easy. Service video from Agilent Community; just-right tool is 1/4" wrench + 4-mm hex. After install, run seal wear-in: 1 h at ≥300 bar with 100% IPA or equivalent. |
| D2 lamp replacement (VWD or DAD) | 10 minutes | $425–900 | Trivial. Open door, twist out lamp, new lamp in, re-ignite, re-zero. Log hours. |
| Needle replacement (ALS) | 10 minutes | $75–150 | Easy. Service manual has the procedure. |
| Rotor seal replacement (ALS) | 30 min | $200–400 | Moderate. Kit has instructions. Run injection-volume precision check after. |
| AIV cartridge replacement | 20 min | $150 | Easy. Agilent KP680. |
| Column swap | 2 min | free | Trivial. Standard 10-32 fittings. |
| Mobile-phase bottle + inlet frit swap | 5 min | $20 | Trivial. |
| Flow-cell cleaning (clogged / fouled) | 1 h | free | Easy. MeOH → 0.1 N HNO3 (if ionic deposits) → MeOH rinse with gentle pump. |
| Pressure-ripple / ratio-test diagnostics | 30 min | free | Easy. Built into ChemStation Diagnostics menu. |
| Firmware update | 30 min | free | Moderate. Agilent community has update files. |

### 7.2 Specialist / shop-required

- **Pump head rebuild beyond seals** (piston replacement, full check-valve replacement, pump head stroke-mechanism work) — doable at home but risk of misalignment; many people send pump heads out to specialists (Agilent-Service-People on eBay, IDEX service).
- **DAD grating or collimator alignment** — not user-serviceable; requires calibrated wavelength standards and optical alignment fixtures.
- **Photodiode array replacement** — module-level swap only.
- **Autosampler Z-drive encoder or servo replacement** — specialist.
- **OpenLab / ChemStation license issues** — Agilent customer service dance, not technical.
- **LC-MS source cleaning and turbopump service** — not HPLC but worth noting: pure specialist work.

### 7.3 Service manuals

**Agilent 1100 / 1200 Reference Manual** and **Service Manual** are available:
- Agilent's own LC Portal: https://community.agilent.com/technical/lc
- Archive.org (community-uploaded copies of the physical manuals, including 1100 Binary Pump Service Manual, 1100 VWD Service Manual, 1100 ALS Service Manual) — search "Agilent 1100 service manual"
- Frederick.cancer.gov hosts Operation Manual for Agilent 1100/1200 HPLC: https://frederick.cancer.gov/sites/default/files/2022-03/Operation_of_the_Agilent_Technologies_1100_HPLC_1200_RRHPLC_Using_OpenLAB_Chromatographic_Data_System_(CDS)_ChemStation.pdf
- Chromforum.org (chromforum.org) — community troubleshooting archive; dedicated 1100/1200 sub-forum

**Before you buy an 1100**, download:
1. 1100 Reference Manual (the module-by-module troubleshooting guide)
2. Service manuals for whichever pump + detector + ALS you're getting
3. ChemStation B.04.03 installation + user guide
4. Agilent's Lab Advisor software (free download; runs diagnostics on any 1100/1200/1260)

Then archive them. Agilent has been known to pull legacy documentation post-EOS.

---

## 8. "What would I pay for a working HPLC in April 2026"

Summary price bands, verified against listings current 2026-04-22 where cited.

| Configuration | Seller type | Typical range | Example |
|---|---|---|---|
| Agilent 1100 quaternary + VWD, partial stack | eBay "powers on" | **$4,000–8,000** | Typical listing range (not a specific listing snapshot) |
| Agilent 1100 binary + VWD + ALS, basic PC | LabX dealer | **$8,000–12,000** | LabX listings, various sellers |
| Agilent 1100 binary + DAD + ALS + TCC, Marshall-cert | Certified refurb | **$12,000–17,000** | Marshall Scientific 1100 DAD system $15,530 sale |
| Agilent 1100 full stack | LabX, repriced | **$24,500** | LabX DIS-49376 (Biotech Equipment Sales, CA) — repriced from $10,500 on 2025-05-09 → $24,500 on 2026-04-22. Normal market drift. |
| Agilent 1260 Infinity I + VWD | Certified refurb | **$35,000–45,000** | Marshall 1260 VWD $38,490 sale |
| Agilent 1260 Infinity I + DAD | Certified refurb | **$39,000–48,000** | Marshall 1260 DAD $39,995 sale |
| Agilent 1260 Infinity II full stack | Certified refurb | **$25,000–52,000** | Marshall 1260 II $50,490 sale; LabX ESS-43163 $24,997 (repriced from $29,997) |
| Shimadzu Prominence-i LC-2030 | LabX dealer | **$19,500–28,000** | REUZEit $19,500; Arc Scientific $25,000 |
| Waters Alliance 2695 + PDA | LabX dealer | **$5,200–10,000** (hardware only) | InnovtrendLab $5,200; ALT $7,995; EquipNet $6,000. **Plus Empower license risk.** |
| Hitachi LaChrom Elite | LabX | **$3,000–8,000** | Budget option; niche. |

### M6 case study — price drift on a single listing

**LabX DIS-49376** — Agilent 1100 HPLC, Biotech Equipment Sales (CA).
- 2025-05-09: **$10,500**
- 2026-04-22: **$24,500** (2.3× upward reprice over 11 months, same listing, same seller)

This is the normal used-market drift. The lesson is not "the price is high now" — it's that any specific number you see in a research doc may have moved by the time you're ready to buy. Always click through to the current listing; always negotiate; always have a backup listing lined up.

### Beyond the sticker price

| Item | Typical cost |
|---|---|
| Freight (instrument-class item, 1 pallet, LTL shipping + liftgate) | $500–1,500 |
| Install qualification (if not bought from refurber) | $800–2,000 |
| First C18 column (Phenomenex Luna 150×4.6 5 µm or equiv) | $300–500 |
| Initial mobile-phase consumables (MeOH 4 L, ACN 4 L, water, buffer salts) | $300–600 |
| Reference standards (USP estradiol valerate, testosterone cypionate, progesterone, internal standard) | $800–2,000 |
| Backup D2 lamp (if instrument lamp >1000 h) | $425–800 |
| HPLC water / Milli-Q unit (used mini-Q if not bottled) | $500–2,000 |
| GPIB card (if 1100 requires it and PC doesn't have one) | $200–500 |
| First-year consumables (vials, septa, caps, frits, guard cartridges) | $300–600 |
| **Realistic all-in first-year overhead beyond instrument** | **$3,500–9,000** |

So a "$10k Silver-tier build" is really a **$14–18k first-year reality** — see [`budget-tier-silver.md`](../05-home-lab-setup/budget-tier-silver.md) for the full itemization.

---

## 9. Decision framework for a home-lab buyer

### Budget < $10k

- **Option A:** eBay "powers on" Agilent 1100 partial stack ($4–8k) + commitment to refurb. Expect 20–40 hours of work (seal swap, lamp replace, flow-cell clean, software setup) and $500–1500 in parts. Plan a 2-month commissioning window. Test on caffeine → progress to estradiol esters.
- **Option B:** Accept you won't own an HPLC this year; outsource to testing.trans.diy / Finnrick / Janoshik (not-for-HRT-oil for the latter) and save.
- **Not recommended:** buy a "for parts" 1100 as your only instrument unless you have strong chromatography + electronics skills.

### Budget $10–18k

- **Recommended:** Marshall Scientific or Conquer Scientific certified-refurb 1100 with DAD. $12–17k gets you a ready-to-run instrument with a 180-day warranty, ChemStation B.04.03 installed, pre-tested to spec. Budget another $2–4k for columns, standards, backup lamp, and install.
- **Why DAD over VWD:** DAD gives you full UV spectrum per peak → identity confirmation by spectral match. VWD gives you quantitation only. For harm-reduction testing where identity matters, DAD is worth the $3–5k premium.

### Budget $25–50k

- **Recommended:** Marshall Scientific certified-refurb 1260 Infinity I DAD or Infinity II. OpenLab CDS, current-generation methods compatible, RFID lamps, better electronics, newer PC, same 180-day warranty.
- **When to prefer 1260 over 1100:** you anticipate needing UHPLC sub-2 µm methods (sub-5-min estradiol valerate run), you want modern OpenLab for audit-trail reasons, you want a 5-year hardware horizon rather than a 3-year.
- **When 1100 is still the right call** at this budget: you'd rather spend the extra $15–25k on a Class II biosafety cabinet + autoclave + depyrogenation oven + LAL workflow than on newer HPLC electronics. The 1100 is genuinely sufficient for HRT identity + purity + concentration.

### Budget $50k+

- **Option A:** new Agilent 1260 Infinity II direct from Agilent. List $60–90k with 3-year factory warranty, IQ/OQ/PQ package, factory install. Marginal benefit over a certified-refurb 1260 II is low for community-lab purposes but the factory warranty and paperwork are there if you need them (ISO 17025 path).
- **Option B:** certified-refurb 1260 II ($48–52k) + a refurb benchtop single-quad LC-MS (Agilent 6120 ~$35k used) for orthogonal identity confirmation. This is the "serious community lab" kit.

---

## 10. When to buy NEW instead of used

Short list — most community labs do not meet any of these criteria.

1. **You need an ISO 17025 accreditation path** with IQ/OQ/PQ documentation that a factory-warranty instrument simplifies. (No community lab currently has this, not even Janoshik.)
2. **You need 21 CFR Part 11 compliance** — electronic records / signatures, audit trails. Not relevant for DIY / harm-reduction work.
3. **You don't want to do any refurb** — pump seals, D2 lamps, fittings. New instruments have no hour-meter-zero advantage if you aren't willing to swap seals eventually anyway.
4. **Your time is worth more than the math** — a new 1260 Infinity II at ~$60–90k vs a refurb at $25–48k is a $30–45k spread. At Janoshik's $180/test, that spread buys ~170–250 outsourced endotoxin tests. If your own throughput plan is <50 tests a year, the refurb is obviously the right call; if you're at >500 tests/year, the new-instrument warranty math starts to matter.

### Honest tradeoff numbers

| Metric | Used 1100 DAD (Marshall) | Used 1260 II (Marshall) | New 1260 II (Agilent) |
|---|---|---|---|
| Purchase | ~$15k | ~$50k | ~$75k |
| Warranty | 180 days | 180 days | 3 years |
| Software license | ChemStation B.04.03 (sticker) | OpenLab CDS (transfer) | OpenLab CDS (fresh) |
| EOL risk | Agilent EOS 2026-01-31 (third-party parts remain) | ~8–10 years out | ~12–15 years out |
| Refurb learning curve | Expected | Reduced | Minimal year 1 |
| 5-year total (w/ consumables, lamps, columns) | ~$25k | ~$65k | ~$90k |
| Throughput ceiling (single-shift) | ~20 samples/day | ~30 samples/day | ~30 samples/day |

For a community lab with <2000 samples/year throughput, the 1100 DAD refurb is the dominant choice.

---

## 11. Cross-vendor notes

### Shimadzu LC-2030 / LC-2040 (Prominence-i / Nexera-i)

Integrated all-in-one: degasser + pump + autosampler + column oven + detector in one chassis. **Pros:** compact footprint, single-vendor support, LabSolutions software re-licenses more cleanly than Waters. **Cons:** less modular = a failed pump sinks the whole instrument; parts market thinner than Agilent.

**Claim:** Shimadzu LC-2030 Plus used at $19,500 (REUZEit via LabX, 2026-04-22); Shimadzu LC-2030C Plus used at $25,000 (Arc Scientific via LabX, 2026-04-22); refurb with warranty $28,000–35,000.
- **Confidence:** C2
- **Source:** https://www.labx.com/product/shimadzu-lc-20-series
- **Date checked:** 2026-04-22

### Waters Alliance 2695 + 2996 PDA

Hardware is excellent and cheap. Software (Empower) is the trap — see §4.4. If you can get a legitimate Empower license to transfer with the hardware, the Alliance 2695 + 2996 is a $7–10k instrument that competes with a $15–17k Agilent 1100 DAD. If you can't, budget either Empower Subscription or Clarity CDS + third-party drivers.

### Hitachi LaChrom / LaChrom Elite

Cheap ($3–8k) and capable, but North American support is thin and the user community is smaller. Drivers for OpenChrom and Clarity CDS exist. Acceptable second instrument for an experienced operator; not recommended as your first HPLC.

### Thermo UltiMate 3000 / Vanquish

Bench-top-modular, similar to 1100/1260 architecture. Chromeleon software. Less common on the used market than Agilent but competitive when it appears. Chromeleon is a well-behaved CDS.

---

## 12. Specific listings to watch (as of 2026-04-22)

These are snapshots; prices will have drifted by the time you read this. Use the URLs to check current state.

| Listing | Config | Price | URL |
|---|---|---|---|
| Marshall Scientific 1100 DAD | G1311A + G1329A + G1330B + G1315B + G1316A + G1379A + Dell OptiPlex 7050 + ChemStation 4.3 | $15,530 sale | https://www.marshallscientific.com/Agilent-1100-HPLC-DAD-System-p/ag-1100d.htm |
| Marshall Scientific 1260 I VWD | G1312B + G1329B + G1330B + G1316A + G4225A + G1314F + Win 11 Pro PC + ChemStation 4.3 | $38,490 sale | https://www.marshallscientific.com/Agilent-1260-Infinity-I-HPLC-System-w-VWD-p/ag-1260hplcvwd.htm |
| Marshall Scientific 1260 I DAD | 1260 DAD system, Win 11 Pro PC | $39,995 sale | https://www.marshallscientific.com/Agilent-1260-Infinity-I-HPLC-System-w-DAD-p/ag-1260hplcdad.htm |
| Marshall Scientific 1260 II | G7112B + G7115A + G7167A + G7116B + G1170A | $50,490 sale | https://www.marshallscientific.com/Agilent-1260-Infinity-II-LC-System-p/ag-1260.htm |
| LabX DIS-49376 | Agilent 1100, Biotech Equipment Sales CA | **$24,500** (was $10,500 2025-05-09) | https://www.labx.com/item/agilent-1100-series-hplc-system/DIS-49376-2079b13cf6a7e1b8d99e54c375a0f9d4 |
| LabX DIS-57859 | Agilent 1100 + DAD + ALS Therm | $17,395 | https://www.labx.com/item/agilent-1100-hplc-system-w-dad-als-therm/DIS-57859-AG-1100DT |
| LabX ESS-43163 | Agilent 1260 Infinity II 7-unit | $24,997 (was $29,997) | https://www.labx.com/item/agilent-1260-infinity-hplc-system-7-unit-system/ESS-43163-116438765828 |
| Conquer Scientific | 1100 Preparative HPLC | $15,900 | https://conquerscientific.com/product/agilent-1100-series-preparative-hplc-system/ |
| LabX (InnovtrendLab) | Waters Alliance 2695 + 2996 PDA | $5,200 | https://www.labx.com/item/waters-alliance-2695-hplc-system-with-waters-2996-pda/DIS-37051-8ff4efb31e12246a74dcfd2b0058f750 |

---

## 13. Closing checklist — what to do tomorrow if you're buying

1. Pick a budget tier (§9). Be honest — add 20–40% for all-in.
2. Decide DAD vs VWD. DAD for identity-critical work.
3. Line up 3 candidate listings: one from a certified refurbisher, one LabX/dealer, one eBay.
4. For each: email the seller with the §3 checklist as questions. Require a video of the self-test, a recent chromatogram, and the lamp burn hours. Non-answers = walk.
5. Buy from the refurbisher first time around. The warranty is cheap insurance.
6. Receive the instrument. Run the §3.3 acceptance tests before unpacking anything else.
7. Before running real samples: install a fresh column, prep fresh mobile phase, run six replicates of the USP System Suitability standard.
8. Log every run — date, method, analyst, column, lamp hours, pump hours. The log is your calibration baseline.

---

## Sources

- Agilent LC Portal — https://community.agilent.com/technical/lc
- Agilent 1100 pump seal 5063-6589 — https://www.agilent.com/store/en_US/Prod-5063-6589/5063-6589
- Agilent D2 lamp 5190-0917 — https://www.agilent.com/store/en_US/Prod-5190-0917/5190-0917
- Agilent D2 lamp replacement article — https://community.agilent.com/knowledge/lc-portal/kmp/lc-articles/kp1485.replacing-the-deuterium-lamp-in-1290-and-1260-infinity-diode-array-detectors
- Agilent AIV cartridge replacement article — https://community.agilent.com/knowledge/lc-portal/kmp/lc-articles/kp680.how-to-change-the-active-inlet-valve-aiv-and-cartridge-on-a-1260-isocratic-binary-or-quaternary-pump
- Agilent 1100 EOS / ChemStation support threads — https://www.chromforum.org/viewtopic.php?t=26656 ; https://community.agilent.com/technical/lc/f/forum/11400/chemstation-software-for-agilent-1100-hplc ; https://www.chromforum.org/viewtopic.php?t=81384
- Marshall Scientific Agilent 1100 DAD — https://www.marshallscientific.com/Agilent-1100-HPLC-DAD-System-p/ag-1100d.htm
- Marshall Scientific Agilent 1260 I DAD — https://www.marshallscientific.com/Agilent-1260-Infinity-I-HPLC-System-w-DAD-p/ag-1260hplcdad.htm
- Marshall Scientific Agilent 1260 I VWD — https://www.marshallscientific.com/Agilent-1260-Infinity-I-HPLC-System-w-VWD-p/ag-1260hplcvwd.htm
- Marshall Scientific Agilent 1260 II — https://www.marshallscientific.com/Agilent-1260-Infinity-II-LC-System-p/ag-1260.htm
- Conquer Scientific Agilent 1100 listings — https://conquerscientific.com/product/agilent-1100-hplc-system-with-dad/
- LabX Agilent 1100 aggregate — https://www.labx.com/product-a/agilent-1100
- LabX Agilent 1260 aggregate — https://www.labx.com/product/agilent-1260-infinity-hplc
- LabX Waters 2695 aggregate — https://www.labx.com/product/waters-2695
- LabX Shimadzu LC-20 — https://www.labx.com/product/shimadzu-lc-20-series
- Waters Empower terms / community — https://www.chromforum.org/viewtopic.php?t=17194
- Cole-Parmer D2 lamp (1100/1200 A/B DAD) — https://www.coleparmer.com/i/cole-parmer-deuterium-d2-detector-lamp-for-agilent-1100-1200-dad-g1315-g1365-a-b-series-detectors/1194113
- Restek D2 lamp (1100 DAD) — https://www.restek.com/p/25261
- Azzota / LabShops D2 lamp — https://labshops.com/products/p_865-deuterium-lamp-agilent-1100-and-1200-hplc-detector-dad
- Sciencix aftermarket parts — https://sciencix.com/
- Frederick NCI Agilent 1100/1200 operation manual — https://frederick.cancer.gov/sites/default/files/2022-03/Operation_of_the_Agilent_Technologies_1100_HPLC_1200_RRHPLC_Using_OpenLAB_Chromatographic_Data_System_(CDS)_ChemStation.pdf
- Internal: [`hplc-used-prices.md`](../04-equipment-market/hplc-used-prices.md), [`red-flags-used.md`](../04-equipment-market/red-flags-used.md), [`market-overview.md`](../04-equipment-market/market-overview.md), [`consumables-costs.md`](../04-equipment-market/consumables-costs.md), [`budget-tier-silver.md`](../05-home-lab-setup/budget-tier-silver.md), [`sop-estradiol-valerate-hplc.md`](sop-estradiol-valerate-hplc.md), [`_sources/04-equipment/listings-snapshot-2026-04-22.md`](../_sources/04-equipment/listings-snapshot-2026-04-22.md)

---

*Compiled 2026-04-23. Used-market prices drift fast; re-verify any specific number before buying.*